Arginase 1 activity worsens lung-protective immunity againstStreptococcus pneumoniaeinfection
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چکیده
منابع مشابه
Correction: Possible Role of Arginase-1 in Concomitant Tumor Immunity
The expression of Adenovirus serotype 2 or serotype 5 (Ad2/5) E1A in tumor cells reduces their tumorigenicity in vivo by enhancing the NK cell mediated and T cell mediated anti-tumor immune response, an activity that correlates with the ability of E1A to bind p300. We determined if E1A could be used as a molecular adjuvant to enhance antigen-specific T cell responses to a model tumor antigen, o...
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Chronic nonhealing wounds in the elderly population are associated with a prolonged and excessive inflammatory response, which is widely hypothesized to impede healing. Previous studies have linked alterations in local L-arginine metabolism, principally mediated by the enzymes arginase (Arg) and inducible nitric oxide synthase (iNOS), to pathological wound healing. Over subsequent years, intere...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2015
ISSN: 0014-2980
DOI: 10.1002/eji.201445419